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Genome-Wide Methylation Analysis Identifies Novel Cpg Loci For Perimembranous Ventricular Septal Defects In Human

31 Jan 2017

Abstract excerpt

AIM: Congenital heart diseases are the most common birth defects worldwide and leading cause of infant mortality. The perimembranous ventricular septal defect is most prevalent. Epigenetics may provide an underlying mechanism of the gene-environment interactions involved. MATERIALS & METHODS: We examined epigenome-wide DNA methylation using the Illumina HumanMethylation450 BeadChip in 84 case children and 196...

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PMID: 28140654
DOI: 10.2217/epi-2016-0093

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