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Article

Non-AUG start codons responsible for ABO weak blood group alleles on initiation mutant backgrounds.

Scientific reports - 31 Jan 2017

Cid Emili, Yamamoto Miyako, Yamamoto Fumiichiro

Abstract excerpt

Histo-blood group ABO gene polymorphism is crucial in transfusion medicine. We studied the activity and subcellular distribution of ABO gene-encoded A glycosyltransferases with N-terminal truncation. We hypothesized that truncated enzymes starting at internal methionines drove the synthesis of oligosaccharide A antigen in those already described alleles that lack a proper translation initiation codon. Not only we...

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Identifiers

PMID: 28139731
DOI: 10.1038/srep41720
PMCID: PMC5282485

Genes

ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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