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Article

Is perturbation in the quaternary structure of bacterial CysE, another regulatory mechanism for cysteine synthesis?

International journal of biological macromolecules - 1 May 2018

Verma Deepali, Gupta Sunita, Kaur Kanwal J, Gupta Vibha

Abstract excerpt

Drug resistance to almost all antibiotics of Shigella flexneri, a major cause of shigellosis in developing countries, necessitates continuous discovery of novel therapeutics. This study reports a structure-function analysis of a potential drug target serine acetyltransferase (CysE), an enzyme of de novo cysteine biosynthesis pathway that is absent in humans. Analysis of CysE sequences of S. flexneri species and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Structure, Quaternary

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Source

Identifiers

PMID: 29366889
DOI: 10.1016/j.ijbiomac.2018.01.076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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