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Article

Identification of amino acids involved in catalytic process of M. tuberculosis GlmU acetyltransferase.

Glycoconjugate journal - 1 Aug 2012

Zhou Yan, Yu Wendan, Zheng Qi, Xin Yi, Ma Yufang

Abstract excerpt

M. tuberculosis GlmU is a bifunctional enzyme with acetyltransferase activity in C-terminus and uridyltransferase activity in N-terminus, and it is involved in the biosynthesis of glycosyl donor UDP-N-acetylglucosamine (UDP-GlcNAc). The crystal structure of M. tuberculosis GlmU clearly determines the active site and catalytic mechanism of GlmU uridyltransferase domain but not succeed in GlmU acetyltransferase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22669463
DOI: 10.1007/s10719-012-9402-5

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