Article
Alterations in Peptidoglycan Cross-Linking Suppress the Secretin Assembly Defect Caused by Mutation of GspA in the Type II Secretion System.
Journal of bacteriology - 15 Apr 2017
Vanderlinde Elizabeth M, Strozen Timothy G, Hernández Sara B, Cava Felipe, Howard S Peter
Abstract excerpt
In Gram-negative bacteria, the peptidoglycan (PG) cell wall is a significant structural barrier for outer membrane protein assembly. In Aeromonas hydrophila, outer membrane multimerization of the type II secretion system (T2SS) secretin ExeD requires the function of the inner membrane assembly factor complex ExeAB. The putative mechanism of the complex involves the reorganization of PG and localization of ExeD,...
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