Article
Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro.
Stem cell research - 1 Mar 2017
Ozaki Masahiro, Iwanami Akio, Nagoshi Narihito, Kohyama Jun, Itakura Go, Iwai Hiroki, Nishimura Soraya, Nishiyama Yuichiro, Kawabata Soya, Sugai Keiko, Iida Tsuyoshi, Matsubayashi Kohei, Isoda Miho, Kashiwagi Rei, Toyama Yoshiaki, Matsumoto Morio, Okano Hideyuki, Nakamura Masaya
Abstract excerpt
To achieve the goal of a first-in-human trial for human induced pluripotent stem cell (hiPSC)-based transplantation for the treatment of various diseases, allogeneic human leukocyte antigen (HLA)-matched hiPSC cell banks represent a realistic tool from the perspective of quality control and cost performance. Furthermore, considering the limited therapeutic time-window for acute injuries, including neurotraumatic...
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