Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway.

Stem cell research & therapy - 22 Aug 2018

Xin Tianyi, Zhang Ting, Li Qian, Yu Tingting, Zhu Yunyan, Yang Ruili, Zhou Yanheng

Abstract excerpt

BACKGROUND: Tooth agenesis, one of the most common developmental anomalies, can affect the function and esthetics of patients. The aim of the present study was to identify genetic clues for familial tooth agenesis and explore the underlying mechanisms, focusing on the role of human dental pulp stem cells (hDPSCs). METHODS: We applied Sanger sequencing to identify the cause of oligodontia in a Chinese family. DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anodontia
Share to Butadienes
Share to Dental Pulp

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to MSX1 Transcription Factor

Share to Nitriles

Share to Sialoglycoproteins

Source

Open in PubMed Open full text

Identifiers

PMID: 30134957
DOI: 10.1186/s13287-018-0965-3
PMCID: PMC6106924

Genes

MSX1
DSPP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway.PMID 30134957Read ↗

A novel MSX1 intronic mutation associated with autosomal dominant non-syndromic oligodontia in a large Chinese family pedigree.Semantic proximity Read ↗

A novel non-stop mutation in MSX1 causing autosomal dominant non-syndromic oligodontia.Semantic proximity Read ↗

Functional Analysis of Ectodysplasin-A Mutations in X-Linked Non-Syndromic Hypodontia and Possible Involvement of X-Chromosome InactivationSemantic proximity Read ↗

Novel MSX1 variants identified in families with nonsyndromic oligodontiaSemantic proximity Read ↗

Novel nonsense mutation in MSX1 causes tooth agenesis with cleft lip in a Chinese family.Semantic proximity Read ↗

Clinical and genetic evaluation of a Chinese family with isolated oligodontia.Semantic proximity Read ↗

Effect of EDA1 Variants on Human Pulp Stem Cell Biology and Odontogenic DifferentiationSemantic proximity Read ↗

Functional analysis of Ectodysplasin-A mutations in X-linked non-syndromic hypodontia and possible involvement of X-chromosome inactivationSemantic proximity Read ↗

Identification of a novel missense mutation of MSX1 gene in Chinese family with autosomal-dominant oligodontia.Semantic proximity Read ↗

Novel missense mutations in PAX9 causing oligodontia.Semantic proximity Read ↗

Non-syndromic Oligodontia with a Novel Mutation of <i>PAX9</i>Semantic proximity Read ↗

Orodental malformations associated with human MSX1 sequence variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.