Article
Global Proteome Changes in the Rat Diaphragm Induced by Endurance Exercise Training.
PloS one - 1 Jan 2017
Sollanek Kurt J, Burniston Jatin G, Kavazis Andreas N, Morton Aaron B, Wiggs Michael P, Ahn Bumsoo, Smuder Ashley J, Powers Scott K
Abstract excerpt
Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in the rapid development of diaphragmatic atrophy and weakness. Importantly, endurance exercise training results in a diaphragmatic phenotype that is protected against ventilator-induced diaphragmatic atrophy and weakness. The mechanisms responsible for this exercise-induced protection...
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