Article
Effect of mutation mechanisms on variant composition and distribution in Caenorhabditis elegans.
PLoS computational biology - 1 Jan 2017
Hwang Ho-Yon, Wang Jiou
Abstract excerpt
Genetic diversity is maintained by continuing generation and removal of variants. While examining over 800,000 DNA variants in wild isolates of Caenorhabditis elegans, we made a discovery that the proportions of variant types are not constant across the C. elegans genome. The variant proportion is defined as the fraction of a specific variant type (e.g. single nucleotide polymorphism (SNP) or indel) within a...
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