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Identification of Mutant Genes and Introgressed Tiger Salamander DNA in the Laboratory Axolotl, Ambystoma mexicanum.

Scientific reports - 31 Jan 2017

Woodcock M Ryan, Vaughn-Wolfe Jennifer, Elias Alexandra, Kump D Kevin, Kendall Katharina Denise, Timoshevskaya Nataliya, Timoshevskiy Vladimir, Perry Dustin W, Smith Jeramiah J, Spiewak Jessica E, Parichy David M, Voss S Randal

Abstract excerpt

The molecular genetic toolkit of the Mexican axolotl, a classic model organism, has matured to the point where it is now possible to identify genes for mutant phenotypes. We used a positional cloning-candidate gene approach to identify molecular bases for two historic axolotl pigment phenotypes: white and albino. White (d/d) mutants have defects in pigment cell morphogenesis and differentiation, whereas albino...

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PMID: 28127056
DOI: 10.1038/s41598-017-00059-1
PMCID: PMC5428337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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