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Article

Crystal Structure of an Invasivity-Associated Domain of SdrE in S. aureus.

PloS one - 1 Jan 2017

Luo Miao, Zhang Xiang, Zhang Shaocheng, Zhang Hongpeng, Yang Wei, Zhu Zhongliang, Chen Ke, Bai Lei, Wei Jie, Huang Ailong, Wang Deqiang

Abstract excerpt

The surface protein SdrE, a microbial surface components recognizing adhesive matrix molecule (MSCRAMM) family protein expressed on the surface of Staphylococcus aureus (S. aureus), can recognize human complement regulator Factor H and C4BP, thus making it a potentially promising vaccine candidate. In this study, SdrE278-591 was found to directly affect S. aureus host cell invasion. Additionally, the crystal...

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Identifiers

PMID: 28125581
DOI: 10.1371/journal.pone.0168814
PMCID: PMC5268492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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