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"Liquid biopsy"-ctDNA detection with great potential and challenges.

1 Sept 2015

Abstract excerpt

Circulating tumor DNA (ctDNA) is now being extensively studied as it is a noninvasive "real-time" biomarker that can provide diagnostic and prognostic information before, during treatment and at progression. These include DNA mutations, epigenetic alterations and other forms of tumor-specific abnormalities such as microsatellite instability (MSI) and loss of heterozygosity (LOH). ctDNA is of great value in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26539452
DOI: 10.3978/j.issn.2305-5839.2015.09.29

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