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Article

Relationship Between Some Single-nucleotide Polymorphism and Response to Hydroxyurea Therapy in Iranian Patients With β-Thalassemia Intermedia.

Journal of pediatric hematology/oncology - 1 May 2017

Karimi Mehran, Zarei Tahereh, Haghpanah Sezaneh, Moghadam Mohamad, Ebrahimi Ahmad, Rezaei Narges, Heidari Ghazaleh, Vazin Afsaneh, Khavari Maryam, Miri Hamid R

Abstract excerpt

OBJECTIVE: To evaluate the possible relationship between hydroxyurea (HU) response and some single-nucleotide polymorphism (SNP) in patients affected by β-thalassemia intermedia. MATERIALS AND METHODS: In this cross-sectional study, 100 β-thalassemia intermedia patients who were taking HU with a dose of 8 to 15 mg/kg body weight per day for a period of at least 6 months were randomly selected between February...

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Identifiers

PMID: 28121747
DOI: 10.1097/MPH.0000000000000779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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