Article
Hyperforin Exhibits Antigenotoxic Activity on Human and Bacterial Cells.
Molecules (Basel, Switzerland) - 21 Jan 2017
Imreova Petronela, Feruszova Jana, Kyzek Stanislav, Bodnarova Kristina, Zduriencikova Martina, Kozics Katarina, Mucaji Pavel, Galova Eliska, Sevcovicova Andrea, Miadokova Eva, Chalupa Ivan
Abstract excerpt
Hyperforin (HF), a substance that accumulates in the leaves and flowers of Hypericum perforatum L. (St. John's wort), consists of a phloroglucinol skeleton with lipophilic isoprene chains. HF exhibits several medicinal properties and is mainly used as an antidepressant. So far, the antigenotoxicity of HF has not been investigated at the level of primary genetic damage, gene mutations, and chromosome aberrations,...
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