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Article

Genotypes and Haplotypes of the Estrogen Receptor α Gene (ESR1) Are Associated With Female-to-Male Gender Dysphoria.

The journal of sexual medicine - 1 Mar 2017

Cortés-Cortés Joselyn, Fernández Rosa, Teijeiro Nerea, Gómez-Gil Esther, Esteva Isabel, Almaraz Mari Cruz, Guillamón Antonio, Pásaro Eduardo

Abstract excerpt

INTRODUCTION: Gender dysphoria, a marked incongruence between one's experienced gender and biological sex, is commonly believed to arise from discrepant cerebral and genital sexual differentiation. With the discovery that estrogen receptor β is associated with female-to-male (FtM) but not with male-to-female (MtF) gender dysphoria, and given estrogen receptor α involvement in central nervous system...

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Source

Identifiers

PMID: 28117266
DOI: 10.1016/j.jsxm.2016.12.234

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genotypes and Haplotypes of the Estrogen Receptor α Gene (ESR1) Are Associated With Female-to-Male Gender Dysphoria.PMID 28117266Read ↗

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