Article
Relationship of long-term prognosis to MMP and TIMP polymorphisms in patients after ST elevation myocardial infarction.
Journal of applied genetics - 1 Aug 2017
Pavkova Goldbergova Monika, Jarkovsky Jiri, Lipkova Jolana, Littnerova Simona, Poloczek Martin, Spinar Jindrich, Kubkova Lenka, Kluz Krystyna, Kala Petr, Manousek Jan, Vasku Anna, Parenica Jiri
Abstract excerpt
The influence of polymorphisms in the large group of MMP and TIMP genes on clinical outcomes in patients after ST elevation myocardial infarction (STEMI) treated with primary PCI was analysed. In total, 550 consecutive Caucasian patients with STEMI were included in the present study, with a median of 32 months. We analysed 19 polymorphisms in the genes coding MMP and TIMP genes. The MMP-1 -519A/G and -422A/T...
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