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Article

Rottlerin-induced autophagy leads to apoptosis in bladder cancer cells

13 Oct 2016

Abstract excerpt

It has been well-established that apoptosis contributes to cancer cell death; however, the role of autophagy in cancer cell death remains unclear. The aim of the present study was to investigate the effects of rottlerin, a traditional Indian medicine, on cell growth inhibition and autophagy in EJ human bladder carcinoma cells in vitro. Cell viability, measured by MTT assay, was found to be suppressed in a dose‑...

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PMID: 28101215
DOI: 10.3892/ol.2016.5255

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