Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA‐27b Targets Gremlin 1 to Modulate Fibrotic Responses in Pulmonary Cells

14 Mar 2014

Abstract excerpt

Fibrosis is a chronic disease characterized by an excessive deposition of scar tissue in the affected organs. A central mediator of this process is transforming growth factor-β (TGF-β), which stimulates the production of extracellular matrix proteins such as collagens. MicroRNAs (miRNAs) have been implicated in both fibrosis as well as in TGF-β signaling, but the extent of their regulation has not been fully...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24633904
DOI: 10.1002/jcb.24809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA‐27b Targets Gremlin 1 to Modulate Fibrotic Responses in Pulmonary CellsPMID 24633904Read ↗

miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathwaySemantic proximity Read ↗

The Antifibrotic Effects and Mechanisms of MicroRNA-26a Action in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Integrated analyses identify the involvement of microRNA-26a in epithelial–mesenchymal transition during idiopathic pulmonary fibrosisSemantic proximity Read ↗

Role of MicroRNAs in TGF-β Signaling Pathway-Mediated Pulmonary FibrosisSemantic proximity Read ↗

MicroRNA in Fibrotic Disorders: A Potential Target for Future TherapeuticsSemantic proximity Read ↗

miR-29 Is a Major Regulator of Genes Associated with Pulmonary FibrosisSemantic proximity Read ↗

Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosisSemantic proximity Read ↗

MicroRNA-326 Regulates Profibrotic Functions of Transforming Growth Factor-β in Pulmonary FibrosisSemantic proximity Read ↗

Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosisSemantic proximity Read ↗

Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulationSemantic proximity Read ↗

miR-335-3p attenuates transforming growth factor beta 1-induced fibrosis by suppressing Thrombospondin 1Semantic proximity Read ↗

miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.