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Article

Antimelanoma Differentiation-associated Gene 5 Antibody: Expanding the Clinical Spectrum in North American Patients with Dermatomyositis.

The Journal of rheumatology - 1 Mar 2017

Moghadam-Kia Siamak, Oddis Chester V, Sato Shinji, Kuwana Masataka, Aggarwal Rohit

Abstract excerpt

OBJECTIVE: To determine the clinical features associated with the antimelanoma differentiation-associated gene 5 antibody (anti-MDA5) in US patients with clinically amyopathic dermatomyositis (CADM) and classic DM. METHODS: Patients with CADM were consecutively selected from the University of Pittsburgh Myositis Database from 1985 to 2013. CADM was defined by a typical DM rash without objective muscle weakness...

Topics

Adult
Autoantibodies
Dermatomyositis
Disease Progression
Female
Humans
Interferon-Induced Helicase, IFIH1
Male
Middle Aged
Phenotype
Symptom Assessment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28089977
DOI: 10.3899/jrheum.160682

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