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Article

Prevalence and clinical significance of anti-MDA5 antibodies in European patients with polymyositis/dermatomyositis.

Clinical and experimental rheumatology - 1 Jan 2000

Ceribelli Angela, Fredi Micaela, Taraborelli Mara, Cavazzana Ilaria, Tincani Angela, Selmi Carlo, Chan Jason Y F, Chan Edward K L, Satoh Minoru, Franceschini Franco

Abstract excerpt

OBJECTIVES: Polymyositis/dermatomyositis (PM/DM) is an autoimmune disease characterised by skin and muscle inflammation, internal organ involvement and serum disease-specific autoantibodies. The recently identified anti-MDA5 (melanoma differentiation-associated gene 5) antibodies are associated with clinically amyopathic DM (CADM), rapidly progressive interstitial lung disease, severe skin manifestations, and...

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PMID: 25151986

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Prevalence and clinical significance of anti-MDA5 antibodies in European patients with polymyositis/dermatomyositis.PMID 25151986Read ↗

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