Article
Association of plasminogen activator inhibitor-1 and vitamin D receptor expression with the risk of keloid disease in a Chinese population.
The Kaohsiung journal of medical sciences - 1 Jan 2017
Gong Zhen-Hua, Ji Jian-Feng, Yang Jun, Xiang Tie, Zhou Chang-Kai, Pan Xuan-Liang, Yao Jian
Abstract excerpt
Keloid disease (KD) is a benign fibroproliferative scarring condition of unknown etiopathogenesis. Plasminogen activator inhibitor-1 (PAI-1) and vitamin D receptor (VDR) have been shown to play important roles in the progression of tissue fibrosis; therefore, both these genes are potential susceptibility genes for KD. We aimed to determine whether the gene expression levels of PAI-1 and VDR are altered in Chinese...
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