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Article

Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 2017

Ueda Mahoko Takahashi, Kurosaki Yohei, Izumi Taisuke, Nakano Yusuke, Oloniniyi Olamide K, Yasuda Jiro, Koyanagi Yoshio, Sato Kei, Nakagawa So

Abstract excerpt

Ebola virus (EBOV) is extremely virulent, and its glycoprotein is necessary for viral entry. EBOV may adapt to its new host humans during outbreaks by acquiring mutations especially in glycoprotein, which allows EBOV to spread more efficiently. To identify these evolutionary selected mutations and examine their effects on viral infectivity, we used experimental-phylogenetic-structural interdisciplinary...

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PMID: 28084671
DOI: 10.1111/gtc.12463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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