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Article

Effects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis.

Journal of neuro-oncology - 1 Mar 2017

Xavier-Magalhães Ana, Oliveira Ana I, de Castro Joana Vieira, Pojo Marta, Gonçalves Céline S, Lourenço Tatiana, Viana-Pereira Marta, Costa Sandra, Linhares Paulo, Vaz Rui, Nabiço Rui, Amorim Júlia, Pinto Afonso A, Reis Rui M, Costa Bruno M

Abstract excerpt

Abnormal expression of the long non-coding RNA HOX transcript antisense intergenic RNA (HOTAIR) is oncogenic in several human cancers, including gliomas. The HOTAIR single nucleotide polymorphisms (SNPs) rs920778 (C > T) and rs12826786 (C > T) present in the intronic enhancer and promoter regions of HOTAIR, respectively, are associated with expression, cancer susceptibility, and patient prognosis in some tumor...

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Identifiers

PMID: 28083786
DOI: 10.1007/s11060-016-2345-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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