Article
Characterization of Three CYP2C19 Gene Variants by MassARRAY and Point of Care Techniques: Experience from a Czech Centre.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2016
Petrek Martin, Kocourkova Lenka, Zizkova Veronika, Nosek Zdenek, Taborsky Milos, Petrkova Jana
Abstract excerpt
Distribution of cytochrome P450 2C19 enzyme gene (CYP2C19) variants affecting metabolism of clopidogrel was determined in 526 Czech patients after percutaneous coronary intervention using MassARRAY genotyping and compared to distribution in other populations of European descent. Fifty-three (10%) patients underwent parallel determination of CYP2C19 genotypes from buccal swabs by a point of care technique with...
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