Rapid and portable, lab-on-chip, point-of-care genotyping for evaluating clopidogrel metabolism.

doi:10.1016/j.cca.2015.10.003

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Article

Rapid and portable, lab-on-chip, point-of-care genotyping for evaluating clopidogrel metabolism.

Clinica chimica acta; international journal of clinical chemistry - 7 Dec 2015

Marziliano Nicola, Notarangelo Maria Francesca, Cereda Marco, Caporale Vittoria, Coppini Lucia, Demola Maria Antonietta, Guidorossi Angela, Crocamo Antonio, Pigazzani Filippo, Boffetti Francesca, del Giudice Federica, Orsini Francesco, Pirola Danilo, Cocci Alessandro, Manzalini Chiara, Casu Gavino, Bianchessi Marco, Ardissino Diego, Merlini Piera Angelica

Abstract excerpt

BACKGROUND: Dual antiplatelet therapy with aspirin and a platelet P2Y12 receptor inhibitors (clopidogrel, prasugrel, ticagrelor) is a cornerstone of antithrombotic treatment in patients with acute coronary syndromes (ACS). Clopidogrel has been the standard of care for nearly a decade; however, its clinical efficacy is influenced by a considerable inter-patient variability in response, clearly associated to...

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PMID: 26453416
DOI: 10.1016/j.cca.2015.10.003

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ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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