Article
Adipose stem cell-derived nanovesicles inhibit emphysema primarily via an FGF2-dependent pathway.
Experimental & molecular medicine - 13 Jan 2017
Kim You-Sun, Kim Ji-Young, Cho RyeonJin, Shin Dong-Myung, Lee Sei Won, Oh Yeon-Mok
Abstract excerpt
Cell therapy using stem cells has produced therapeutic benefits in animal models of COPD. Secretory mediators are proposed as one mechanism for stem cell effects because very few stem cells engraft after injection into recipient animals. Recently, nanovesicles that overcome the disadvantages of natural exosomes have been generated artificially from cells. We generated artificial nanovesicles from adipose-derived...
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