Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bioinspired Nanovesicles Convert the Skeletal Endothelium-Associated Secretory Phenotype to Treat Osteoporosis.

ACS nano - 26 Jul 2022

Cui Yongzhi, Li Zhongying, Guo Yuanyuan, Qi Xiangbei, Yang Yuehua, Jia Xiong, Li Rui, Shi Jingyu, Gao Weihang, Ren Zhengwei, Liu Guohui, Ye Qingsong, Zhang Zhiping, Fu Dehao

Abstract excerpt

Recently, bone marrow endothelial cells (BMECs) were found to play an important role in regulating bone homeostasis. However, few studies utilized BMECs to treat bone metabolic diseases including osteoporosis. Here, we reported bioinspired nanovesicles (BNVs) prepared from human induced pluripotent stem cells-derived endothelial cells under hypoxia culture through an extrusion approach. Abundant membrane C-X-C...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Endothelium

Share to Induced Pluripotent Stem Cells

Share to Osteogenesis

Share to Osteoporosis

Share to Phenotype

Source

Identifiers

PMID: 35801837
DOI: 10.1021/acsnano.2c03781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bioinspired Nanovesicles Convert the Skeletal Endothelium-Associated Secretory Phenotype to Treat Osteoporosis.PMID 35801837Read ↗

M2 macrophages-derived exosomes for osteonecrosis of femoral head treatment: modulating neutrophil extracellular traps formation and endothelial phenotype transitionSemantic proximity Read ↗

Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentialsSemantic proximity Read ↗

Bone-targeted extracellular vesicles from mesenchymal stem cells for osteoporosis therapySemantic proximity Read ↗

Unlocking the potential of exosomes: a breakthrough in the theranosis of degenerative orthopaedic diseasesSemantic proximity Read ↗

Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cellsSemantic proximity Read ↗

The Role of Exosomes in Bone Remodeling: Implications for Bone Physiology and DiseaseSemantic proximity Read ↗

Exosomal Manf originated from endothelium regulated osteoclast differentiation by down- regulating NF-κB signaling pathwaySemantic proximity Read ↗

Exosomes from young plasma alleviate osteoporosis through miR-217-5p-regulated osteogenesis of bone marrow mesenchymal stem cellSemantic proximity Read ↗

A Review Into the Insights of the Role of Endothelial Progenitor Cells on Bone BiologySemantic proximity Read ↗

<span class="word">A <span class="word">Comprehensive <span class="word">Review <span class="word">of <span class="word">Engineered <span class="word">Bone <span class="word">Marrow <span class="word">Mesenchymal <span class="word">Stem <span class="word">Cell-<span class="word">Derived <span class="word">Exosomes <span class="word">as <span class="word">Nanotheranostic <span class="word">Platforms <span class="word">for <span class="word">Acute <span class="word">and <span class="word">Chronic…Semantic proximity Read ↗

Bone-derived exosomesSemantic proximity Read ↗

The role and mechanism of exosomes from umbilical cord mesenchymal stem cells in inducing osteogenesis and preventing osteoporosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.