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Article

Hsp90 and Physiological Stress Are Linked to Autonomous Transposon Mobility and Heritable Genetic Change in Nematodes.

Genome biology and evolution - 1 Dec 2016

Ryan Calen P, Brownlie Jeremy C, Whyard Steve

Abstract excerpt

Transposable elements (TEs) have been recognized as potentially powerful drivers of genomic evolutionary change, but factors affecting their mobility and regulation remain poorly understood. Chaperones such as Hsp90 buffer environmental perturbations by regulating protein conformation, but are also part of the PIWI-interacting RNA pathway, which regulates genomic instability arising from mobile TEs in the...

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Share to Caenorhabditis elegans
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28082599
DOI: 10.1093/gbe/evw284
PMCID: PMC5521727

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