Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.

doi:10.1002/mds.26896

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Article

Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Apr 2017

Visanji Naomi P, Bhudhikanok Grace S, Mestre Tiago A, Ghate Taneera, Udupa Kaviraj, AlDakheel Amaal, Connolly Barbara S, Gasca-Salas Carmen, Kern Drew S, Jain Jennifer, Slow Elizabeth J, Faust-Socher Achinoam, Kim Sam, Azhu Valappil Ruksana, Kausar Farah, Rogaeva Ekaterina, William Langston J, Tanner Caroline M, Schüle Birgitt, Lang Anthony E, Goldman Samuel M, Marras Connie

Abstract excerpt

BACKGROUND: Heart rate variability is reduced in idiopathic PD, indicating cardiac autonomic dysfunction likely resulting from peripheral autonomic synucleinopathy. Little is known about heart rate variability in leucine-rich repeat kinase 2-associated PD. OBJECTIVES: This study investigated heart rate variability in LRRK2-associated PD. METHODS: Resting electrocardiograms were obtained from 20 individuals with...

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PMID: 28071824
DOI: 10.1002/mds.26896

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