Article
Features of the Arabidopsis recombination landscape resulting from the combined loss of sequence variation and DNA methylation.
Proceedings of the National Academy of Sciences of the United States of America - 2 Oct 2012
Colomé-Tatché Maria, Cortijo Sandra, Wardenaar René, Morgado Lionel, Lahouze Benoit, Sarazin Alexis, Etcheverry Mathilde, Martin Antoine, Feng Suhua, Duvernois-Berthet Evelyne, Labadie Karine, Wincker Patrick, Jacobsen Steven E, Jansen Ritsert C, Colot Vincent, Johannes Frank
Abstract excerpt
The rate of meiotic crossing over (CO) varies considerably along chromosomes, leading to marked distortions between physical and genetic distances. The causes underlying this variation are being unraveled, and DNA sequence and chromatin states have emerged as key factors. However, the extent to which the suppression of COs within the repeat-rich pericentromeric regions of plant and mammalian chromosomes results...
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