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Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer.

European urology - 1 Jun 2017

Christensen Emil, Birkenkamp-Demtröder Karin, Nordentoft Iver, Høyer Søren, van der Keur Kirstin, van Kessel Kim, Zwarthoff Ellen, Agerbæk Mads, Ørntoft Torben Falck, Jensen Jørgen Bjerggaard, Dyrskjøt Lars

Abstract excerpt

BACKGROUND: Disease surveillance in patients with bladder cancer is important for early diagnosis of progression and metastasis and for optimised treatment. OBJECTIVE: To develop urine and plasma assays for disease surveillance for patients with FGFR3 and PIK3CA tumour mutations. DESIGN, SETTING, AND PARTICIPANTS: Droplet digital polymerase chain reaction (ddPCR) assays were developed and tumour DNA from two...

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Share to Circulating Tumor DNA
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Invasiveness

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Share to Receptor, Fibroblast Growth Factor, Type 3

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Source

Identifiers

PMID: 28069289
DOI: 10.1016/j.eururo.2016.12.016

Genes

FGFR3

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