Article
Combination of uterine natural killer cell immunoglobulin receptor haplotype and trophoblastic HLA-C ligand influences the risk of pregnancy loss: a retrospective cohort analysis of direct embryo genotyping data from euploid transfers.
Fertility and sterility - 1 Mar 2017
Morin Scott J, Treff Nathan R, Tao Xin, Scott Richard T, Franasiak Jason M, Juneau Caroline R, Maguire Marcy, Scott Richard T
Abstract excerpt
OBJECTIVE: To compare maternal uterine natural killer cell immunoglobulin receptor (KIR) genotype and haplotype frequencies between patients whose euploid single-embryo transfer resulted in pregnancy loss and those that resulted in delivery and to determine if the risk of pregnancy loss was affected by the HLA-C genotype content in the embryo. DESIGN: Retrospective cohort. SETTING: Academic research center....
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