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Article

Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlled by Endothelin 3 and Requires Regulation of Ednrb by SOX10 and ZEB2.

Gastroenterology - 1 Apr 2017

Watanabe Yuli, Stanchina Laure, Lecerf Laure, Gacem Nadjet, Conidi Andrea, Baral Viviane, Pingault Veronique, Huylebroeck Danny, Bondurand Nadege

Abstract excerpt

BACKGROUND & AIMS: Maintenance and differentiation of progenitor cells in the developing enteric nervous system are controlled by molecules such as the signaling protein endothelin 3 (EDN3), its receptor (the endothelin receptor type B [EDNRB]), and the transcription factors SRY-box 10 (SOX10) and zinc finger E-box binding homeobox 2 (ZEB2). We used enteric progenitor cell (EPC) cultures and mice to study the...

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Source

Identifiers

PMID: 28063956
DOI: 10.1053/j.gastro.2016.12.034

Genes

EDN3
ZEB2
EDNRB
SOX10
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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