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Article

Estimation of cell-free circulating EGFR mutation concentration predicts outcomes in NSCLC patients treated with EGFR-TKIs.

Oncotarget - 21 Feb 2017

Zhu Yan-Juan, Zhang Hai-Bo, Liu Yi-Hong, Zhang Fu-Li, Zhu Ya-Zhen, Li Yong, Bai Jian-Ping, Liu Li-Rong, Qu Yan-Chun, Qu Xin, Chen Xian, Li Yan, Zheng Guang-Juan

Abstract excerpt

Detection of circulating tumor DNA using droplet digital polymerase chain reaction (ddPCR) is a highly-sensitive, minimally invasive alternative to serial biopsies for assessment and management of cancer. We used ddPCR to assess the utility of measuring plasma concentrations of common epidermal growth factor receptor (EGFR) mutations (L858R, exon 19 deletion, and T790M) in 57 non-small cell lung cancer (NSCLC)...

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Identifiers

PMID: 28061461
DOI: 10.18632/oncotarget.14490
PMCID: PMC5355088

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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