Article
Characterization of VNTRs Within the Entire Region of SLC6A3 and Its Association with Hypertension.
DNA and cell biology - 1 Mar 2017
Kim Won-Tae, Lee Se-Ra, Roh Yun-Gil, Kim Seung Il, Choi Yung Hyun, Mun Mi-Hye, Jeong Mi-So, Koh Sang Seok, Leem Sun-Hee
Abstract excerpt
The dopamine transporter SLC6A3 (DAT1) mediates uptake of dopamine into presynaptic terminals. In addition, in previous reports, hypertensive rats were associated with DAT gene, but the genetic association with SLC6A3 and hypertension is still unknown. We examined the distribution of variable number of tandem repeats (VNTRs) and conducted polymorphic analysis of the entire region of SLC6A3. Ten VNTR regions...
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