Article
Association of HLA-DRB1 and HLA-DQB1 with red-blood-cell alloimmunization in the Czech population.
Vox sanguinis - 1 Feb 2017
Maluskova A, Mrazek F, Pauliskova M, Kovarova P, Koristka M, Jindra P, Cermakova Z
Abstract excerpt
BACKGROUND AND OBJECTIVES: Alloimmune antibodies against red-blood-cell (RBC) antigens induced in susceptible individuals (responders) by transfusion, pregnancy or transplantation may have serious clinical consequences. The aim of this study was to investigate association of alloimmunization against selected RBC antigens with HLA-Class II. MATERIALS AND METHODS: A total of 230 responders (106 monoresponders and...
Topics
- Adult
- Alleles
- Czech Republic
- Erythrocytes
- Female
- Gene Frequency
- Genotype
- HLA-DQ beta-Chains
- HLA-DRB1 Chains
- Haplotypes
- Humans
- Isoantibodies
