Article
Improved method for prioritization of disease associated lncRNAs based on ceRNA theory and functional genomics data.
Oncotarget - 17 Jan 2017
Wang Peng, Guo Qiuyan, Gao Yue, Zhi Hui, Zhang Yan, Liu Yue, Zhang Jizhou, Yue Ming, Guo Maoni, Ning Shangwei, Zhang Guangmei, Li Xia
Abstract excerpt
Although several computational models that predict disease-associated lncRNAs (long non-coding RNAs) exist, only a limited number of disease-associated lncRNAs are known. In this study, we mapped lncRNAs to their functional genomics context using competing endogenous RNAs (ceRNAs) theory. Based on the criteria that similar lncRNAs are likely involved in similar diseases, we proposed a disease lncRNA...
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