Article
Identification of Genotype 2 HCV in Serotype-1 Hepatitis C Patients Unresponsive to Daclatasvir plus Asunaprevir Treatment.
The Tohoku journal of experimental medicine - 1 Jan 2017
Inoue Jun, Kanno Atsushi, Wakui Yuta, Miura Masahito, Kobayashi Tomoo, Morosawa Tatsuki, Kogure Takayuki, Kakazu Eiji, Ninomiya Masashi, Fujisaka Yasuyuki, Umetsu Teruyuki, Takai Satoshi, Nakamura Takuya, Shimosegawa Tooru
Abstract excerpt
It is important to determine the genotypes or serotypes of hepatitis C virus (HCV) in patients before treatment with direct-acting antiviral agents (DAAs), because the effects of DAAs differ among genotypes. In Japan, two tests for HCV typing are available clinically, but only serotyping, not genotyping, is approved by the public health insurance. Although most serotype-1 Japanese patients are infected with...
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