Article
Sequence conservation of Plasmodium vivax glutamate dehydrogenase among Korean isolates and its application in seroepidemiology.
Malaria journal - 3 Jan 2017
Seol Bomin, Shin Hyun-Il, Kim Jung-Yeon, Jeon Bo-Young, Kang Yoon-Joong, Pak Jhang-Ho, Kim Tong-Soo, Lee Hyeong-Woo
Abstract excerpt
BACKGROUND: Glutamate dehydrogenase of malaria parasites (pGDH) is widely used in rapid diagnostic tests for malaria. Variation in the pGDH gene among Korean isolates of Plasmodium vivax was analysed, and a recombinant pGDH protein was evaluated for use as antigens for the serodiagnosis of vivax malaria. METHODS: Genomic DNA was purified from blood samples of 20 patients and the pGDH gene of P. vivax was...
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