Article
Genetic variation of aldolase from Korean isolates of Plasmodium vivax and its usefulness in serodiagnosis.
Malaria journal - 8 May 2012
Kim Jung-Yeon, Kim Hyung-Hwan, Shin Hyun-ll, Sohn Youngjoo, Kim Hyuck, Lee Sang-Wook, Lee Won-Ja, Lee Hyeong-Woo
Abstract excerpt
BACKGROUND: The malaria aldolase is widely used as rapid diagnostic test (RDT), but the efficacy in aspect of its serological effectiveness in diagnosis is not known. The genetic variation of Korean isolates was analysed and recombinant aldolase was evaluated as a serological antigen in Plasmodium vivax malaria. METHODS: Genomic DNA was purified and the aldolase gene of P. vivax from 25 patients' blood samples...
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