Article
The Different T-cell Receptor Repertoires in Breast Cancer Tumors, Draining Lymph Nodes, and Adjacent Tissues.
Cancer immunology research - 1 Feb 2017
Wang Ting, Wang Changxi, Wu Jinghua, He Chenyang, Zhang Wei, Liu Jiayun, Zhang Ruifang, Lv Yonggang, Li Yongping, Zeng Xiaojing, Cao Hongzhi, Zhang Xiuqing, Xu Xun, Huang Chen, Wang Ling, Liu Xiao
Abstract excerpt
T lymphocytes infiltrate the microenvironment of breast cancer tumors and play a pivotal role in tumor immune surveillance. Relationships between the T-cell receptors (TCR) borne by T cells within tumors, in the surrounding tissues, and in draining lymph nodes are largely unexplored in human breast cancer. Consequently, information about the relative extent of possible T-cell exchange between these tissues is...
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