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Article

Variation of lifespan in multiple strains, and effects of dietary restriction and BmFoxO on lifespan in silkworm, Bombyx mori.

Oncotarget - 31 Jan 2017

Song Jiangbo, Tang Dongmei, Li Zhiquan, Tong Xiaoling, Zhang Jianfei, Han Minjin, Hu Hai, Lu Cheng, Dai Fangyin

Abstract excerpt

Established animal models have accelerated our understanding of the mechanisms involved in lifespan determination. However, more experimental animals are required to clarify the complex mechanisms behind the phenomena of aging and lifespan. In this study, we reported the variation of lifespan in nine distinct silkworm strains. Lifespan correlated significantly with BmFoxO gene expression in the representative...

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Identifiers

PMID: 28038468
DOI: 10.18632/oncotarget.14235
PMCID: PMC5352321

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