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AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis

24 Dec 2016

Abstract excerpt

// Abhishek A. Singh 1 , Amit Mandoli 1 , Koen H.M. Prange 1 , Marko Laakso 2 , Joost H.A. Martens 1 1 Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands 2 Genome Scale Biology Research Program, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland Correspondence to: Joost Martens,...

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PMID: 28030795
DOI: 10.18632/oncotarget.14150

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