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Article

[Determination of EGFR gene somatic mutations in tissues and plasma of patients with advanced non-small cell lung cancer].

Biomeditsinskaia khimiia - 1 Nov 2016

Brovkina O I, Gordiev M G, Toropovskiy A N, Khodyrev D S, Enikeev R F, Gusev O A, Shigapova L H, Nikitin A G

Abstract excerpt

The presence of activating mutations in the EGFR gene influences cell proliferation, angiogenesis, and increases metastatic ability; it has a significant impact on the choice of medical therapy of non-small cell lung cancer (NSCLC). The use of targeted therapy with tyrosine kinase inhibitors requires performance of appropriate genetic tests. The aim of this study was to design a real-time PCR-based diagnostic kit...

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Source

Identifiers

PMID: 28026806
DOI: 10.18097/PBMC20166206638

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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