Article
Behavioral characterization of female zinc transporter 3 (ZnT3) knockout mice.
Behavioural brain research - 15 Mar 2017
Thackray Sarah E, McAllister Brendan B, Dyck Richard H
Abstract excerpt
Zinc is an important element in all cells of the body, having structural, enzymatic, and regulatory functions. In some neurons, zinc is loaded into synaptic vesicles by zinc transporter 3 (ZnT3) and released into the synaptic cleft, where it can modulate neuronal function. ZnT3 knockout (KO) mice lack ZnT3 and thus lack synaptic zinc. Previous studies have examined the behavioral phenotype of ZnT3 KO mice, mostly...
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