Article
Identification of a synonymous variant in TRIM59 gene for gastric cancer risk in a Chinese population.
Oncotarget - 14 Feb 2017
Luo Dakui, Wang Younan, Huan Xiangkun, Huang Chi, Yang Chao, Fan Hao, Xu Zekuan, Yang Li
Abstract excerpt
Tripartite motif 59 (TRIM59) is a novel oncogenic driver in gastric cancer (GC) that is implicated in disease progression as well as dismal survival. Genetic variants in peculiar gene are likely candidates for conferring hereditary susceptibility. The role of TRIM59 polymorphism in predicting the risk of malignant diseases and its relevance to TRIM59 expression have not been discussed. Using a HapMap tagSNPs...
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