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Article

Translational misreading, amino acid misincorporation and misinterpretations. The case of the flavocytochrome b2 H373Q variant.

Biochimica et biophysica acta. Proteins and proteomics - 1 Mar 2017

Elhoul Mouna Ben, Machillot Paul, Benoît Mireille, Lederer Florence

Abstract excerpt

Amino acid misincorporation during protein synthesis occurs naturally at a low level. Protein sequence errors, depending on the level and the nature of the misincorporation, can have various consequences. When site-directed mutagenesis is used as a tool for understanding the role of a side chain in enzyme catalysis, misincorporation in a variant with intrinsically low activity may lead to misinterpretations...

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Identifiers

PMID: 28007443
DOI: 10.1016/j.bbapap.2016.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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