Article
Galectin-3 and Its Genetic Variation rs4644 Modulate Enterovirus 71 Infection.
PloS one - 1 Jan 2016
Huang Wen-Chan, Chen Hung-Lin, Chen Huan-Yuan, Peng Kuan-Po, Lee Yungling, Huang Li-Min, Chang Luan-Yin, Liu Fu-Tong
Abstract excerpt
Galectin-3, a chimeric type β-galactoside-binding protein, is known to modulate viral infection; however, its role in enterovirus 71 (EV71) infection has not been investigated. We generated galectin-3 null rhabdomyosarcoma (RD) cells and evaluated whether EV71 infection would be affected. In galectin-3 null cells, the released and intracellular EV71 viral loads were suppressed after 24 h of infection, and cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.