Article
A Data Fusion Approach to Enhance Association Study in Epilepsy.
PloS one - 1 Jan 2016
Marini Simone, Limongelli Ivan, Rizzo Ettore, Malovini Alberto, Errichiello Edoardo, Vetro Annalisa, Da Tan, Zuffardi Orsetta, Bellazzi Riccardo
Abstract excerpt
Among the scientific challenges posed by complex diseases with a strong genetic component, two stand out. One is unveiling the role of rare and common genetic variants; the other is the design of classification models to improve clinical diagnosis and predictive models for prognosis and personalized therapies. In this paper, we present a data fusion framework merging gene, domain, pathway and protein-protein...
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