Article
The SAMP8 mouse for investigating memory and the role of insulin in the brain.
Experimental gerontology - 1 Aug 2017
Rhea Elizabeth M, Banks William A
Abstract excerpt
SAMP8 mice exhibit changes that commonly occur with normal aging late in life, but do so at a much earlier age. These changes include impairments in learning and memory as early as 8months of age and so the SAMP8 is a useful model to investigate those age-related brain changes that may affect cognition. As brain insulin signaling and memory decline with aging, the SAMP8 model is useful for investigating these...
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